Antimicrobial Effect of Cassia alataLeaf Extracts on Fungal Isolates from Tinea Infections
نویسندگان
چکیده
Dermatophytoses are caused by fungi in the genera Microsprum, Trichophyton and Epidermophyton. Africans use extracts of medicinal plants to treat dermatophytosis. This study aimed determine vitro antifungal activity crude leaf extract Cassia alata on fungal isolates from dermatophytosis lesions. Subjects with suspected lesions were recruited for study. Skin scrapings obtained microscopy culture. Isolates identified macroscopically microscopically. Fresh leaves plucked authenticated a Botanist. Aqueous alcohol extraction was done using Soxhlet extractor. subjected leave testing disc diffusion methods. A total 50 subjects comprising 28(56.0%) males 22(44.0%) females male female ratio 2.5: 1. The prevalence dermatophytes infection 14(28.0%). rubrum most encountered (42.8%). Males 10(71.4%) more infected than 4(28.5%). susceptibility rates anfungals range between 0 100% 30(78.6%) Griseofulvin. aqueous effective 33.3% - 83.3% ethanolic 16.7% 50.0%. susceptible 50µg/mL 50% while 25.0% veruccosum E. floccosum resistant extracts. had activities against dermatophytes.
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ژورنال
عنوان ژورنال: Tropical Journal of Natural Product Research
سال: 2023
ISSN: ['2616-0684', '2616-0692']
DOI: https://doi.org/10.26538/tjnpr/v7i5.29